Dynamic association of the plastid localized cysteine synthase complex is vital for efficient cysteine production, photosynthesis, and granal thylakoid formation in transgenic tobacco | Wirtz, M., Leemhuis, W. & Hell, R. | | | |
Walking 200 min per day keeps the bariatric surgeon away | Pfaff, D.H., Poschet, G., Hell, R., Szendrodi, J. & Teleman, A.A. | | | |
Differential modulation of Target of Rapamycin activity under single and combined iron and sulfur deficiency in tomato plants | Coppa, E., Vigani, G., Aref, R., Savatin, D., Bigini, V., Hell, R. & Astolfi, S. | | | |
Accumulation of acetaldehyde in aldh2.1(-/-) zebrafish causes increased retinal angiogenesis and impaired glucose metabolism | Wohlfart, D.P., Lou, B., Middel, C.S., Morgenstern, J., Fleming, T., Sticht, C., Hausser, I., Hell, R., Hammes, H.P., Szendrodi, J., Nawroth, P.P. & Kroll, J. | | | |
HYPK promotes the activity of the N(alpha)-acetyltransferase A complex to determine proteostasis of nonAc-X(2)/N-degron-containing proteins | Miklankova, P., Linster, E., Boyer, J.B., Weidenhausen, J., Mueller, J., Armbruster, L., Lapouge, K., De La Torre, C., Bienvenut, W., Sticht, C., Mann, M., Meinnel, T., Sinning, I., Giglione, C., Hell, R. & Wirtz, M. | | | |
Cotranslational N-degron masking by acetylation promotes proteome stability in plants | Linster, E., Forero Ruiz, F.L., Miklankova, P., Ruppert, T., Mueller, J., Armbruster, L., Gong, X., Serino, G., Mann, M., Hell, R. & Wirtz, M. | | | |
Discriminative Long-Distance Transport of Selenate and Selenite Triggers Glutathione Oxidation in Specific Subcellular Compartments of Root and Shoot Cells in Arabidopsis | Khan, M.S., Soyk, A., Wolf, I., Peter, M., Meyer, A.J., Rausch, T., Wirtz, M. & Hell, R. | | Front Plant Sci: 13, 894479 | |
Pre-analytical processing of plasma and serum samples for combined proteome and metabolome analysis | Gegner, H.M., Naake, T., Dugourd, A., Muller, T., Czernilofsky, F., Kliewer, G., Jager, E., Helm, B., Kunze-Rohrbach, N., Klingmuller, U., Hopf, C., Muller-Tidow, C., Dietrich, S., Saez-Rodriguez, J., Huber, W., Hell, R., Poschet, G. & Krijgsveld, J. | | Front Mol Biosci: 9, 961448 | |
Deep Metabolic Profiling Assessment of Tissue Extraction Protocols for Three Model Organisms | Gegner, H.M., Mechtel, N., Heidenreich, E., Wirth, A., Cortizo, F.G., Bennewitz, K., Fleming, T., Andresen, C., Freichel, M., Teleman, A.A., Kroll, J., Hell, R. & Poschet, G. | | | |
The plant TOR kinase tunes autophagy and meristem activity for nutrient stress-induced developmental plasticity | Dong, Y., Aref, R., Forieri, I., Schiel, D., Leemhuis, W., Meyer, C., Hell, R. & Wirtz, M. | | Plant Cell: 34, 3814-3829 | |
Metabolite Profiling in Arabidopsis thaliana with Moderately Impaired Photorespiration Reveals Novel Metabolic Links and Compensatory Mechanisms of Photorespiration | Timm, S., Nunes-Nesi, A., Florian, A., Eisenhut, M., Morgenthal, K., Wirtz, M., Hell, R., Weckwerth, W., Hagemann, M., Fernie, A.R. & Bauwe, H. | | | |
A molecular switch in sulfur metabolism to reduce arsenic and enrich selenium in rice grain | Sun, S.K., Xu, X., Tang, Z., Tang, Z., Huang, X.Y., Wirtz, M., Hell, R. & Zhao, F.J. | | | |
GSNOR Contributes to Demethylation and Expression of Transposable Elements and Stress-Responsive Genes | Rudolf, E.E., Huther, P., Forne, I., Georgii, E., Han, Y., Hell, R., Wirtz, M., Imhof, A., Becker, C., Durner, J. & Lindermayr, C. | | | |
Reduced Acrolein Detoxification in akr1a1a Zebrafish Mutants Causes Impaired Insulin Receptor Signaling and Microvascular Alterations | Qi, H., Schmohl, F., Li, X., Qian, X., Tabler, C.T., Bennewitz, K., Sticht, C., Morgenstern, J., Fleming, T., Volk, N., Hausser, I., Heidenreich, E., Hell, R., Nawroth, P.P. & Kroll, J. | | Adv Sci (Weinh): 8, e2101281 | |
The function of glutaredoxin GRXS15 is required for lipoyl-dependent dehydrogenases in mitochondria | Moseler, A., Kruse, I., Maclean, A.E., Pedroletti, L., Franceschetti, M., Wagner, S., Wehler, R., Fischer-Schrader, K., Poschet, G., Wirtz, M., Dormann, P., Hildebrandt, T.M., Hell, R., Schwarzlander, M., Balk, J. & Meyer, A.J. | | Plant Physiol: 186, 1507-1525 | |
Abrogating GPT2 in triple-negative breast cancer inhibits tumor growth and promotes autophagy | Mitra, D., Vega-Rubin-de-Celis, S., Royla, N., Bernhardt, S., Wilhelm, H., Tarade, N., Poschet, G., Buettner, M., Binenbaum, I., Borgoni, S., Vetter, M., Kantelhardt, E.J., Thomssen, C., Chatziioannou, A., Hell, R., Kempa, S., Muller-Decker, K. & Wiemann, S. | | Int J Cancer: 148, 1993-2009 | |
Disruption of the N(?)-Acetyltransferase NatB Causes Sensitivity to Reductive Stress in Arabidopsis thaliana | Huber, M., Armbruster, L., Etherington, R.D., De La Torre, C., Hawkesford, M.J., Sticht, C., Gibbs, D.J., Hell, R. & Wirtz, M. | | Front Plant Sci: 12, 799954 | |
A Low Level of NaCl Stimulates Plant Growth by Improving Carbon and Sulfur Assimilation in Arabidopsis thaliana | Hongqiao, L., Suyama, A., Mitani-Ueno, N., Hell, R. & Maruyama-Nakashita, A. | | | |
A Novel UPLC-MS/MS Method Identifies Organ-Specific Dipeptide Profiles | Heidenreich, E., Pfeffer, T., Kracke, T., Mechtel, N., Nawroth, P., Hoffmann, G.F., Schmitt, C.P., Hell, R., Poschet, G. & Peters, V. | | | |
Micrografting Provides Evidence for Systemic Regulation of Sulfur Metabolism between Shoot and Root | Forieri, I., Aref, R., Wirtz, M. & Hell, R. | | | |
Sulfur metabolic engineering enhances cadmium stress tolerance and root to shoot iron translocation in Brassica napus L | Rajab, H., Khan, M.S., Wirtz, M., Malagoli, M., Qahar, F. & Hell, R. | | Plant Physiol Biochem: 152, 32-43 | |
Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination | Nietzel, T., Mostertz, J., Ruberti, C., Nee, G., Fuchs, P., Wagner, S., Moseler, A., Muller-Schussele, S.J., Benamar, A., Poschet, G., Buttner, M., Moller, I.M., Lillig, C.H., Macherel, D., Wirtz, M., Hell, R., Finkemeier, I., Meyer, A.J., Hochgrafe, F. & Schwarzlander, M. | | Proc Natl Acad Sci U S A: 117, 741-751 | |
Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans | Lou, B., Boger, M., Bennewitz, K., Sticht, C., Kopf, S., Morgenstern, J., Fleming, T., Hell, R., Yuan, Z., Nawroth, P.P. & Kroll, J. | | | |
The Arabidopsis N(?) -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response | Linster, E., Layer, D., Bienvenut, W.V., Dinh, T.V., Weyer, F.A., Leemhuis, W., Brünje, A., Hoffrichter, M., Miklankova, P., Kopp, J., Lapouge, K., Sindlinger, J., Schwarzer, D., Meinnel, T., Finkemeier, I., Giglione, C., Hell, R., Sinning, I. & Wirtz, M. | | | |
Regulation of Gluconeogenesis by Aldo-keto-reductase 1a1b in Zebrafish | Li, X., Schmohl, F., Qi, H., Bennewitz, K., Tabler, C.T., Poschet, G., Hell, R., Volk, N., Poth, T., Hausser, I., Morgenstern, J., Fleming, T., Nawroth, P.P. & Kroll, J. | | | |
Prognostic associations of circulating phytoestrogens and biomarker changes in long-term survivors of postmenopausal breast cancer | Jaskulski, S., Jung, A.Y., Huebner, M., Poschet, G., Hell, R., Husing, A., Gonzalez-Maldonado, S., Behrens, S., Obi, N., Becher, H. & Chang-Claude, J. | | Nutr Cancer: 72, 1155-1169 | |
NatB-Mediated N-Terminal Acetylation Affects Growth and Biotic Stress Responses | Huber, M., Bienvenut, W.V., Linster, E., Stephan, I., Armbruster, L., Sticht, C., Layer, D., Lapouge, K., Meinnel, T., Sinning, I., Giglione, C., Hell, R. & Wirtz, M. | | Plant Physiol: 182, 792-806 | |
Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation | Bienvenut, W.V., Brunje, A., Boyer, J.B., Muhlenbeck, J.S., Bernal, G., Lassowskat, I., Dian, C., Linster, E., Dinh, T.V., Koskela, M.M., Jung, V., Seidel, J., Schyrba, L.K., Ivanauskaite, A., Eirich, J., Hell, R., Schwarzer, D., Mulo, P., Wirtz, M., Meinnel, T., Giglione, C. & Finkemeier, I. | | | |
NAA50 Is an Enzymatically Active N (?)-Acetyltransferase That Is Crucial for Development and Regulation of Stress Responses | Armbruster, L., Linster, E., Boyer, J.B., Brünje, A., Eirich, J., Stephan, I., Bienvenut, W.V., Weidenhausen, J., Meinnel, T., Hell, R., Sinning, I., Finkemeier, I., Giglione, C. & Wirtz, M. | | Plant Physiol: 183, 1502-1516 | |
Plant glutathione biosynthesis revisited: redox-mediated activation of glutamylcysteine ligase does not require homo-dimerization | Yang, Y., Lenherr, E.D., Gromes, R., Wang, S., Wirtz, M., Hell, R., Peskan-Berghofer, T., Scheffzek, K. & Rausch, T. | | Biochem J: 476, 1191-1203 | |
Sulfate-Induced Stomata Closure Requires the Canonical ABA Signal Transduction Machinery | Rajab, H., Khan, M.S., Malagoli, M., Hell, R. & Wirtz, M. | | | |
Pyrophosphate modulates plant stress responses via SUMOylation | Patir-Nebioglu, M.G., Andres, Z., Krebs, M., Fink, F., Drzewicka, K., Stankovic-Valentin, N., Segami, S., Schuck, S., Buttner, M., Hell, R., Maeshima, M., Melchior, F. & Schumacher, K. | | | |
Arabidopsis glutathione reductase 2 is indispensable in plastids, while mitochondrial glutathione is safeguarded by additional reduction and transport systems | Marty, L., Bausewein, D., Muller, C., Bangash, S.A.K., Moseler, A., Schwarzlander, M., Muller-Schussele, S.J., Zechmann, B., Riondet, C., Balk, J., Wirtz, M., Hell, R., Reichheld, J.P. & Meyer, A.J. | | New Phytol: 224, 1569-1584 | |
Staphylococcus aureus Uses the Bacilliredoxin (BrxAB)/Bacillithiol Disulfide Reductase (YpdA) Redox Pathway to Defend Against Oxidative Stress Under Infections | Linzner, N., Loi, V.V., Fritsch, V.N., Tung, Q.N., Stenzel, S., Wirtz, M., Hell, R., Hamilton, C.J., Tedin, K., Fulde, M. & Antelmann, H. | | Front Microbiol: 10, 1355 | |
Serum Concentration of Genistein, Luteolin and Colorectal Cancer Prognosis | Jiang, R., Poschet, G., Owen, R., Celik, M., Jansen, L., Hell, R., Hoffmeister, M., Brenner, H. & Chang-Claude, J. | | | |
Impact of pulsed UV-B stress exposure on plant performance: How recovery periods stimulate secondary metabolism while reducing adaptive growth attenuation | Holl, J., Lindner, S., Walter, H., Joshi, D., Poschet, G., Pfleger, S., Ziegler, T., Hell, R., Bogs, J. & Rausch, T. | | Plant Cell Environ: 42, 801-814 | |
Distribution of control in the sulfur assimilation in Arabidopsis thaliana depends on environmental conditions | Feldman-Salit, A., Veith, N., Wirtz, M., Hell, R. & Kummer, U. | | New Phytol: 222, 1392-1404 | |
The Arabidopsis THADA homologue modulates TOR activity and cold acclimation | Dong, Y., Teleman, A.A., Jedmowski, C., Wirtz, M. & Hell, R. | | Plant Biol (Stuttg): 21 Suppl 1, 77-83 | |
SULTR3s Function in Chloroplast Sulfate Uptake and Affect ABA Biosynthesis and the Stress Response | Chen, Z., Zhao, P.X., Miao, Z.Q., Qi, G.F., Wang, Z., Yuan, Y., Ahmad, N., Cao, M.J., Hell, R., Wirtz, M. & Xiang, C.B. | | Plant Physiol: 180, 593-604 | |
The Recovery from Sulfur Starvation Is Independent from the mRNA Degradation Initiation Enzyme PARN in Arabidopsis | Armbruster, L., Uslu, V.V., Wirtz, M. & Hell, R. | | | |
Glucocorticoid deficiency causes transcriptional and post-transcriptional reprogramming of glutamine metabolism | Weger, M., Weger, B.D., Gorling, B., Poschet, G., Yildiz, M., Hell, R., Luy, B., Akcay, T., Guran, T., Dickmeis, T., Muller, F. & Krone, N. | | EBioMedicine: 36, 376-389 | |
Sulfur Partitioning between Glutathione and Protein Synthesis Determines Plant Growth | Speiser, A., Silbermann, M., Dong, Y., Haberland, S., Uslu, V.V., Wang, S., Bangash, S.A.K., Reichelt, M., Meyer, A.J., Wirtz, M. & Hell, R. | | Plant Physiol: 177, 927-937 | |
Author Correction: BCAT1 restricts ?KG levels in AML stem cells leading to IDH(mut)-like DNA hypermethylation | Raffel, S., Falcone, M., Kneisel, N., Hansson, J., Wang, W., Lutz, C., Bullinger, L., Poschet, G., Nonnenmacher, Y., Barnert, A., Bahr, C., Zeisberger, P., Przybylla, A., Sohn, M., Tönjes, M., Erez, A., Adler, L., Jensen, P., Scholl, C., Fröhling, S., Cocciardi, S., Wuchter, P., Thiede, C., Flörcken, A., Westermann, J., Ehninger, G., Lichter, P., Hiller, K., Hell, R., Herrmann, C., Ho, A.D., Krijgsveld, J., Radlwimmer, B. & Trumpp, A. | | | |
Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart | Jabs, M., Rose, A.J., Lehmann, L.H., Taylor, J., Moll, I., Sijmonsma, T.P., Herberich, S.E., Sauer, S.W., Poschet, G., Federico, G., Mogler, C., Weis, E.M., Augustin, H.G., Yan, M., Gretz, N., Schmid, R.M., Adams, R.H., Grone, H.J., Hell, R., Okun, J.G., Backs, J., Nawroth, P.P., Herzig, S. & Fischer, A. | | Circulation: 137, 2592-2608 | |
Sulfate is Incorporated into Cysteine to Trigger ABA Production and Stomatal Closure | Batool, S., Uslu, V.V., Rajab, H., Ahmad, N., Waadt, R., Geiger, D., Malagoli, M., Xiang, C.B., Hedrich, R., Rennenberg, H., Herschbach, C., Hell, R. & Wirtz, M. | | Plant Cell: 30, 2973-2987 | |
Strigolactone- and Karrikin-Independent SMXL Proteins Are Central Regulators of Phloem Formation | Wallner, E.S., Lopez-Salmeron, V., Belevich, I., Poschet, G., Jung, I., Grunwald, K., Sevilem, I., Jokitalo, E., Hell, R., Helariutta, Y., Agusti, J., Lebovka, I. & Greb, T. | | | |
Branched-chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype | Silva, L.S., Poschet, G., Nonnenmacher, Y., Becker, H.M., Sapcariu, S., Gaupel, A.C., Schlotter, M., Wu, Y., Kneisel, N., Seiffert, M., Hell, R., Hiller, K., Lichter, P. & Radlwimmer, B. | | | |
BCAT1 restricts ?KG levels in AML stem cells leading to IDHmut-like DNA hypermethylation | Raffel, S., Falcone, M., Kneisel, N., Hansson, J., Wang, W., Lutz, C., Bullinger, L., Poschet, G., Nonnenmacher, Y., Barnert, A., Bahr, C., Zeisberger, P., Przybylla, A., Sohn, M., Tönjes, M., Erez, A., Adler, L., Jensen, P., Scholl, C., Fröhling, S., Cocciardi, S., Wuchter, P., Thiede, C., Flörcken, A., Westermann, J., Ehninger, G., Lichter, P., Hiller, K., Hell, R., Herrmann, C., Ho, A.D., Krijgsveld, J., Radlwimmer, B. & Trumpp, A. | | | |
The redox-sensitive module of cyclophilin 20-3, 2-cysteine peroxiredoxin and cysteine synthase integrates sulfur metabolism and oxylipin signaling in the high light acclimation response | Muller, S.M., Wang, S., Telman, W., Liebthal, M., Schnitzer, H., Viehhauser, A., Sticht, C., Delatorre, C., Wirtz, M., Hell, R. & Dietz, K.J. | | | |
Drought-Enhanced Xylem Sap Sulfate Closes Stomata by Affecting ALMT12 and Guard Cell ABA Synthesis | Malcheska, F., Ahmad, A., Batool, S., Muller, H.M., Ludwig-Muller, J., Kreuzwieser, J., Randewig, D., Hansch, R., Mendel, R.R., Hell, R., Wirtz, M., Geiger, D., Ache, P., Hedrich, R., Herschbach, C. & Rennenberg, H. | | Plant Physiol: 174, 798-814 | |
P(II) Protein-Derived FRET Sensors for Quantification and Live-Cell Imaging of 2-Oxoglutarate | Luddecke, J., Francois, L., Spat, P., Watzer, B., Chilczuk, T., Poschet, G., Hell, R., Radlwimmer, B. & Forchhammer, K. | | | |
The glyceraldehyde-3-phosphate dehydrogenase GapDH of Corynebacterium diphtheriae is redox-controlled by protein S-mycothiolation under oxidative stress | Hillion, M., Imber, M., Pedre, B., Bernhardt, J., Saleh, M., Loi, V.V., Maass, S., Becher, D., Astolfi Rosado, L., Adrian, L., Weise, C., Hell, R., Wirtz, M., Messens, J. & Antelmann, H. | | | |
Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress | Hillion, M., Bernhardt, J., Busche, T., Rossius, M., Maass, S., Becher, D., Rawat, M., Wirtz, M., Hell, R., Ruckert, C., Kalinowski, J. & Antelmann, H. | | | |
Nothing in Biology Makes Sense But in the Light of Redox Regulation | | | Plant Cell Physiol: 58, 1823-1825 | |
Apoplastic gamma-glutamyl transferase activity encoded by GGT1 and GGT2 is important for vegetative and generative development | Giaretta, S., Prasad, D., Forieri, I., Vamerali, T., Trentin, A.R., Wirtz, M., Hell, R. & Masi, A. | | Plant Physiol Biochem: 115, 44-56 | |
System analysis of metabolism and the transcriptome in Arabidopsis thaliana roots reveals differential co-regulation upon iron, sulfur and potassium deficiency | Forieri, I., Sticht, C., Reichelt, M., Gretz, N., Hawkesford, M.J., Malagoli, M., Wirtz, M. & Hell, R. | | Plant Cell Environ: 40, 95-107 | |
Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids | Weger, B.D., Weger, M., Gorling, B., Schink, A., Gobet, C., Keime, C., Poschet, G., Jost, B., Krone, N., Hell, R., Gachon, F., Luy, B. & Dickmeis, T. | | | |
Integration of light and metabolic signals for stem cell activation at the shoot apical meristem | Pfeiffer, A., Janocha, D., Dong, Y., Medzihradszky, A., Schone, S., Daum, G., Suzaki, T., Forner, J., Langenecker, T., Rempel, E., Schmid, M., Wirtz, M., Hell, R. & Lohmann, J.U. | | | |
MSL1 is a mechanosensitive ion channel that dissipates mitochondrial membrane potential and maintains redox homeostasis in mitochondria during abiotic stress | Lee, C.P., Maksaev, G., Jensen, G.S., Murcha, M.W., Wilson, M.E., Fricker, M., Hell, R., Haswell, E.S., Millar, A.H. & Sweetlove, L.J. | | | |
ROS-Mediated Inhibition of S-nitrosoglutathione Reductase Contributes to the Activation of Anti-oxidative Mechanisms | Kovacs, I., Holzmeister, C., Wirtz, M., Geerlof, A., Frohlich, T., Romling, G., Kuruthukulangarakoola, G.T., Linster, E., Hell, R., Arnold, G.J., Durner, J. & Lindermayr, C. | | | |
Nuclear Localised MORE SULPHUR ACCUMULATION1 Epigenetically Regulates Sulphur Homeostasis in Arabidopsis thaliana | Huang, X.Y., Chao, D.Y., Koprivova, A., Danku, J., Wirtz, M., Muller, S., Sandoval, F.J., Bauwe, H., Roje, S., Dilkes, B., Hell, R., Kopriva, S. & Salt, D.E. | | | |
Ectopically expressed glutaredoxin ROXY19 negatively regulates the detoxification pathway in Arabidopsis thaliana | Huang, L.J., Li, N., Thurow, C., Wirtz, M., Hell, R. & Gatz, C. | | | |
MTHFD1 controls DNA methylation in Arabidopsis | Groth, M., Moissiard, G., Wirtz, M., Wang, H., Garcia-Salinas, C., Ramos-Parra, P.A., Bischof, S., Feng, S., Cokus, S.J., John, A., Smith, D.C., Zhai, J., Hale, C.J., Long, J.A., Hell, R., Diaz de la Garza, R.I. & Jacobsen, S.E. | | | |
Drought stress in maize causes differential acclimation responses of glutathione and sulfur metabolism in leaves and roots | Ahmad, N., Malagoli, M., Wirtz, M. & Hell, R. | | | |
Relation between chemotaxis and consumption of amino acids in bacteria | Yang, Y., A, M.P., Hofler, C., Poschet, G., Wirtz, M., Hell, R. & Sourjik, V. | | Mol Microbiol: 96, 1272-1282 | |
Two N-terminal acetyltransferases antagonistically regulate the stability of a nod-like receptor in Arabidopsis | Xu, F., Huang, Y., Li, L., Gannon, P., Linster, E., Huber, M., Kapos, P., Bienvenut, W., Polevoda, B., Meinnel, T., Hell, R., Giglione, C., Zhang, Y., Wirtz, M., Chen, S. & Li, X. | | Plant Cell: 27, 1547-1562 | |
Mitochondrial Dihydrolipoyl Dehydrogenase Activity Shapes Photosynthesis and Photorespiration of Arabidopsis thaliana | Timm, S., Wittmiss, M., Gamlien, S., Ewald, R., Florian, A., Frank, M., Wirtz, M., Hell, R., Fernie, A.R. & Bauwe, H. | | Plant Cell: 27, 1968-1984 | |
Characterization of the serine acetyltransferase gene family of Vitis vinifera uncovers differences in regulation of OAS synthesis in woody plants | Tavares, S., Wirtz, M., Beier, M.P., Bogs, J., Hell, R. & Amancio, S. | | | |
Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis | Linster, E., Stephan, I., Bienvenut, W.V., Maple-Grodem, J., Myklebust, L.M., Huber, M., Reichelt, M., Sticht, C., Moller, S.G., Meinnel, T., Arnesen, T., Giglione, C., Hell, R. & Wirtz, M. | | | |
Editorial: Frontiers of Sulfur Metabolism in Plant Growth, Development, and Stress Response | Kopriva, S., Talukdar, D., Takahashi, H., Hell, R., Sirko, A., D'Souza, S.F. & Talukdar, T. | | | |
Molecular identification and functional characterization of the first N?-acetyltransferase in plastids by global acetylome profiling | Dinh, T.V., Bienvenut, W.V., Linster, E., Feldman-Salit, A., Jung, V.A., Meinnel, T., Hell, R., Giglione, C. & Wirtz, M. | | Proteomics: 15, 2426-2435 | |
Thiol switches in redox regulation of chloroplasts: balancing redox state, metabolism and oxidative stress | | | | |
Sulfide detoxification in plant mitochondria | Birke, H., Hildebrandt, T.M., Wirtz, M. & Hell, R. | | Methods Enzymol: 555, 271-286 | |
The role of compartment-specific cysteine synthesis for sulfur homeostasis during H2S exposure in Arabidopsis | Birke, H., De Kok, L.J., Wirtz, M. & Hell, R. | | Plant Cell Physiol: 56, 358-367 | |
The significance of cysteine synthesis for acclimation to high light conditions | Speiser, A., Haberland, S., Watanabe, M., Wirtz, M., Dietz, K.J., Saito, K. & Hell, R. | | | |
Affinity Purification of O-Acetylserine(thiol)lyase from Chlorella sorokiniana by Recombinant Proteins from Arabidopsis thaliana | Salbitani, G., Wirtz, M., Hell, R. & Carfagna, S. | | | |
Diversity and regulation of ATP sulfurylase in photosynthetic organisms | Prioretti, L., Gontero, B., Hell, R. & Giordano, M. | | | |
Evidence for several cysteine transport mechanisms in the mitochondrial membranes of Arabidopsis thaliana | Lee, C.P., Wirtz, M. & Hell, R. | | Plant Cell Physiol: 55, 64-73 | |
The mitochondrial sulfur dioxygenase ETHYLMALONIC ENCEPHALOPATHY PROTEIN1 is required for amino acid catabolism during carbohydrate starvation and embryo development in Arabidopsis | Krüßel, L., Junemann, J., Wirtz, M., Birke, H., Thornton, J.D., Browning, L.W., Poschet, G., Hell, R., Balk, J., Braun, H.P. & Hildebrandt, T.M. | | Plant Physiol: 165, 92-104 | |
Sulfate availability affects ABA levels and germination response to ABA and salt stress in Arabidopsis thaliana | Cao, M.J., Wang, Z., Zhao, Q., Mao, J.L., Speiser, A., Wirtz, M., Hell, R., Zhu, J.K. & Xiang, C.B. | | | |
Redesign of genetically encoded biosensors for monitoring mitochondrial redox status in a broad range of model eukaryotes | Albrecht, S.C., Sobotta, M.C., Bausewein, D., Aller, I., Hell, R., Dick, T.P. & Meyer, A.J. | | J Biomol Screen: 19, 379-386 | |
Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis | Sauter, M., Moffatt, B., Saechao, M.C., Hell, R. & Wirtz, M. | | | |
Toward new perspectives on the interaction of iron and sulfur metabolism in plants | Forieri, I., Wirtz, M. & Hell, R. | | | |
SULTR3;1 is a chloroplast-localized sulfate transporter in Arabidopsis thaliana | Cao, M.J., Wang, Z., Wirtz, M., Hell, R., Oliver, D.J. & Xiang, C.B. | | | |
Successful fertilization requires the presence of at least one major O-acetylserine(thiol)lyase for cysteine synthesis in pollen of Arabidopsis | Birke, H., Heeg, C., Wirtz, M. & Hell, R. | | Plant Physiol: 163, 959-972 | |
Mitochondrial cysteine synthase complex regulates O-acetylserine biosynthesis in plants | Wirtz, M., Beard, K.F., Lee, C.P., Boltz, A., Schwarzlander, M., Fuchs, C., Meyer, A.J., Heeg, C., Sweetlove, L.J., Ratcliffe, R.G. & Hell, R. | | J Biol Chem: 287, 27941-27947 | |
Recycling of methylthioadenosine is essential for normal vascular development and reproduction in Arabidopsis | Waduwara-Jayabahu, I., Oppermann, Y., Wirtz, M., Hull, Z.T., Schoor, S., Plotnikov, A.N., Hell, R., Sauter, M. & Moffatt, B.A. | | Plant Physiol: 158, 1728-1744 | |
Targeted systems biology profiling of tomato fruit reveals coordination of the Yang cycle and a distinct regulation of ethylene biosynthesis during postclimacteric ripening | Van de Poel, B., Bulens, I., Markoula, A., Hertog, M.L., Dreesen, R., Wirtz, M., Vandoninck, S., Oppermann, Y., Keulemans, J., Hell, R., Waelkens, E., De Proft, M.P., Sauter, M., Nicolai, B.M. & Geeraerd, A.H. | | Plant Physiol: 160, 1498-1514 | |
Transcriptome profiling of genes differentially modulated by sulfur and chromium identifies potential targets for phytoremediation and reveals a complex S-Cr interplay on sulfate transport regulation in B. juncea | Schiavon, M., Galla, G., Wirtz, M., Pilon-Smits, E.A., Telatin, V., Quaggiotti, S., Hell, R., Barcaccia, G. & Malagoli, M. | | J Hazard Mater: 239-240, 192-205 | |
Effects of fou8/fry1 mutation on sulfur metabolism: is decreased internal sulfate the trigger of sulfate starvation response? | Lee, B.R., Huseby, S., Koprivova, A., Chételat, A., Wirtz, M., Mugford, S.T., Navid, E., Brearley, C., Saha, S., Mithen, R., Hell, R., Farmer, E.E. & Kopriva, S. | | | |
Improved sulfur nutrition provides the basis for enhanced production of sulfur-containing defense compounds in Arabidopsis thaliana upon inoculation with Alternaria brassicicola | Kruse, C., Haas, F.H., Jost, R., Reiser, B., Reichelt, M., Wirtz, M., Gershenzon, J., Schnug, E. & Hell, R. | | J Plant Physiol: 169, 740-743 | |
Vacuolar nicotianamine has critical and distinct roles under iron deficiency and for zinc sequestration in Arabidopsis | Haydon, M.J., Kawachi, M., Wirtz, M., Hillmer, S., Hell, R. & Kramer, U. | | | |
Allosterically gated enzyme dynamics in the cysteine synthase complex regulate cysteine biosynthesis in Arabidopsis thaliana | Feldman-Salit, A., Wirtz, M., Lenherr, E.D., Throm, C., Hothorn, M., Scheffzek, K., Hell, R. & Wade, R.C. | | | |
The relevance of compartmentation for cysteine synthesis in phototrophic organisms | Birke, H., Muller, S.J., Rother, M., Zimmer, A.D., Hoernstein, S.N., Wesenberg, D., Wirtz, M., Krauss, G.J., Reski, R. & Hell, R. | | Protoplasma: 249 Suppl 2, S147-155 | |
Cysteine biosynthesis, in concert with a novel mechanism, contributes to sulfide detoxification in mitochondria of Arabidopsis thaliana | Birke, H., Haas, F.H., De Kok, L.J., Balk, J., Wirtz, M. & Hell, R. | | | |
Generation of Se-fortified broccoli as functional food: impact of Se fertilization on S metabolism | Hsu, F.C., Wirtz, M., Heppel, S.C., Bogs, J., Kramer, U., Khan, M.S., Bub, A., Hell, R. & Rausch, T. | | Plant Cell Environ: 34, 192-207 | |
Molecular Biology, Biochemistry and Cellular Physiology of Cysteine Metabolism in Arabidopsis thaliana | | | Arabidopsis Book: 9, e0154 | |
Evidence for a SAL1-PAP chloroplast retrograde pathway that functions in drought and high light signaling in Arabidopsis | Estavillo, G.M., Crisp, P.A., Pornsiriwong, W., Wirtz, M., Collinge, D., Carrie, C., Giraud, E., Whelan, J., David, P., Javot, H., Brearley, C., Hell, R., Marin, E. & Pogson, B.J. | | Plant Cell: 23, 3992-4012 | |
Sultr4;1 mutant seeds of Arabidopsis have an enhanced sulphate content and modified proteome suggesting metabolic adaptations to altered sulphate compartmentalization | Zuber, H., Davidian, J.C., Wirtz, M., Hell, R., Belghazi, M., Thompson, R. & Gallardo, K. | | | |
The seed composition of Arabidopsis mutants for the group 3 sulfate transporters indicates a role in sulfate translocation within developing seeds | Zuber, H., Davidian, J.C., Aubert, G., Aimé, D., Belghazi, M., Lugan, R., Heintz, D., Wirtz, M., Hell, R., Thompson, R. & Gallardo, K. | | Plant Physiol: 154, 913-926 | |
Enzymes of cysteine synthesis show extensive and conserved modifications patterns that include N(?)-terminal acetylation | Wirtz, M., Heeg, C., Samami, A.A., Ruppert, T. & Hell, R. | | Amino Acids: 39, 1077-1086 | |
Structure and function of the hetero-oligomeric cysteine synthase complex in plants | Wirtz, M., Birke, H., Heeg, C., Muller, C., Hosp, F., Throm, C., Konig, S., Feldman-Salit, A., Rippe, K., Petersen, G., Wade, R.C., Rybin, V., Scheffzek, K. & Hell, R. | | J Biol Chem: 285, 32810-32817 | |
Overexpression of serine acetlytransferase produced large increases in O-acetylserine and free cysteine in developing seeds of a grain legume | Tabe, L., Wirtz, M., Molvig, L., Droux, M. & Hell, R. | | | |
Sulfite reductase defines a newly discovered bottleneck for assimilatory sulfate reduction and is essential for growth and development in Arabidopsis thaliana | Khan, M.S., Haas, F.H., Samami, A.A., Gholami, A.M., Bauer, A., Fellenberg, K., Reichelt, M., Hansch, R., Mendel, R.R., Meyer, A.J., Wirtz, M. & Hell, R. | | Plant Cell: 22, 1216-1231 | |
Inhibition of 5'-methylthioadenosine metabolism in the Yang cycle alters polyamine levels, and impairs seedling growth and reproduction in Arabidopsis | Bürstenbinder, K., Waduwara, I., Schoor, S., Moffatt, B.A., Wirtz, M., Minocha, S.C., Oppermann, Y., Bouchereau, A., Hell, R. & Sauter, M. | | | |
SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers | Roeder, S., Dreschler, K., Wirtz, M., Cristescu, S.M., van Harren, F.J., Hell, R. & Piechulla, B. | | Plant Mol Biol: 70, 535-546 | |
Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites | Mugford, S.G., Yoshimoto, N., Reichelt, M., Wirtz, M., Hill, L., Mugford, S.T., Nakazato, Y., Noji, M., Takahashi, H., Kramell, R., Gigolashvili, T., Flügge, U.I., Wasternack, C., Gershenzon, J., Hell, R., Saito, K. & Kopriva, S. | | | |
The NADPH-dependent thioredoxin system constitutes a functional backup for cytosolic glutathione reductase in Arabidopsis | Marty, L., Siala, W., Schwarzlander, M., Fricker, M.D., Wirtz, M., Sweetlove, L.J., Meyer, Y., Meyer, A.J., Reichheld, J.P. & Hell, R. | | Proc Natl Acad Sci U S A: 106, 9109-9114 | |
The analysis of Arabidopsis nicotianamine synthase mutants reveals functions for nicotianamine in seed iron loading and iron deficiency responses | Klatte, M., Schuler, M., Wirtz, M., Fink-Straube, C., Hell, R. & Bauer, P. | | Plant Physiol: 150, 257-271 | |
A mechanistic model of the cysteine synthase complex | Feldman-Salit, A., Wirtz, M., Hell, R. & Wade, R.C. | | | |
Dynamic plastid redox signals integrate gene expression and metabolism to induce distinct metabolic states in photosynthetic acclimation in Arabidopsis | Bräutigam, K., Dietzel, L., Kleine, T., Ströher, E., Wormuth, D., Dietz, K.J., Radke, D., Wirtz, M., Hell, R., Dörmann, P., Nunes-Nesi, A., Schauer, N., Fernie, A.R., Oliver, S.N., Geigenberger, P., Leister, D. & Pfannschmidt, T. | | Plant Cell: 21, 2715-2732 | |
Non-invasive topology analysis of membrane proteins in the secretory pathway | Brach, T., Soyk, S., Muller, C., Hinz, G., Hell, R., Brandizzi, F. & Meyer, A.J. | | | |
Interactions between chromium and sulfur metabolism in Brassica juncea | Schiavon, M., Pilon-Smits, E.A., Wirtz, M., Hell, R. & Malagoli, M. | | J Environ Qual: 37, 1536-1545 | |
Differential regulation of the expression of two high-affinity sulfate transporters, SULTR1.1 and SULTR1.2, in Arabidopsis | Rouached, H., Wirtz, M., Alary, R., Hell, R., Arpat, A.B., Davidian, J.C., Fourcroy, P. & Berthomieu, P. | | Plant Physiol: 147, 897-911 | |
Restricting glutathione biosynthesis to the cytosol is sufficient for normal plant development | Pasternak, M., Lim, B., Wirtz, M., Hell, R., Cobbett, C.S. & Meyer, A.J. | | | |
Analysis of the Arabidopsis O-acetylserine(thiol)lyase gene family demonstrates compartment-specific differences in the regulation of cysteine synthesis | Heeg, C., Kruse, C., Jost, R., Gutensohn, M., Ruppert, T., Wirtz, M. & Hell, R. | | | |
Mitochondrial serine acetyltransferase functions as a pacemaker of cysteine synthesis in plant cells | Haas, F.H., Heeg, C., Queiroz, R., Bauer, A., Wirtz, M. & Hell, R. | | Plant Physiol: 148, 1055-1067 | |
Dominant-negative modification reveals the regulatory function of the multimeric cysteine synthase protein complex in transgenic tobacco | | | | |
Chromate differentially affects the expression of a high-affinity sulfate transporter and isoforms of components of the sulfate assimilatory pathway in Zea mays (L.) | Schiavon, M., Wirtz, M., Borsa, P., Quaggiotti, S., Hell, R. & Malagoli, M. | | Plant Biol (Stuttg): 9, 662-671 | |
OsMTN encodes a 5'-methylthioadenosine nucleosidase that is up-regulated during submergence-induced ethylene synthesis in rice (Oryza sativa L.) | Rzewuski, G., Cornell, K.A., Rooney, L., Bürstenbinder, K., Wirtz, M., Hell, R. & Sauter, M. | | | |
Redox-sensitive GFP in Arabidopsis thaliana is a quantitative biosensor for the redox potential of the cellular glutathione redox buffer | Meyer, A.J., Brach, T., Marty, L., Kreye, S., Rouhier, N., Jacquot, J.P. & Hell, R. | | | |
Sulphite oxidase as key enzyme for protecting plants against sulphur dioxide | Lang, C., Popko, J., Wirtz, M., Hell, R., Herschbach, C., Kreuzwieser, J., Rennenberg, H., Mendel, R.R. & Hänsch, R. | | Plant Cell Environ: 30, 447-455 | |
Sulfur-enhanced defence: effects of sulfur metabolism, nitrogen supply, and pathogen lifestyle | Kruse, C., Jost, R., Lipschis, M., Kopp, B., Hartmann, M. & Hell, R. | | Plant Biol (Stuttg): 9, 608-619 | |
gamma-Glutamyl transpeptidase GGT4 initiates vacuolar degradation of glutathione S-conjugates in Arabidopsis | Grzam, A., Martin, M.N., Hell, R. & Meyer, A.J. | | FEBS Lett: 581, 3131-3138 | |
The role of methionine recycling for ethylene synthesis in Arabidopsis | Bürstenbinder, K., Rzewuski, G., Wirtz, M., Hell, R. & Sauter, M. | | | |
Functional analysis of the cysteine synthase protein complex from plants: structural, biochemical and regulatory properties | | | J Plant Physiol: 163, 273-286 | |
Vacuolar sequestration of glutathione S-conjugates outcompetes a possible degradation of the glutathione moiety by phytochelatin synthase | Grzam, A., Tennstedt, P., Clemens, S., Hell, R. & Meyer, A.J. | | FEBS Lett: 580, 6384-6390 | |
Glutathione homeostasis and redox-regulation by sulfhydryl groups | | | Photosynth Res: 86, 435-457 | |
Expression profiling of metabolic genes in response to methyl jasmonate reveals regulation of genes of primary and secondary sulfur-related pathways in Arabidopsis thaliana | Jost, R., Altschmied, L., Bloem, E., Bogs, J., Gershenzon, J., Hahnel, U., Hansch, R., Hartmann, T., Kopriva, S., Kruse, C., Mendel, R.R., Papenbrock, J., Reichelt, M., Rennenberg, H., Schnug, E., Schmidt, A., Textor, S., Tokuhisa, J., Wachter, A., Wirtz, M., Rausch, T. & Hell, R. | | Photosynth Res: 86, 491-508 | |
Sulfur metabolism in plants and algae--a case study for an integrative scientific approach | | | Photosynth Res: 86, 297-298 | |
Retrograde plastid redox signals in the expression of nuclear genes for chloroplast proteins of Arabidopsis thaliana | Fey, V., Wagner, R., Braütigam, K., Wirtz, M., Hell, R., Dietzmann, A., Leister, D., Oelmüller, R. & Pfannschmidt, T. | | J Biol Chem: 280, 5318-5328 | |
O-acetylserine (thiol) lyase: an enigmatic enzyme of plant cysteine biosynthesis revisited in Arabidopsis thaliana | Wirtz, M., Droux, M. & Hell, R. | | | |
Regulation of sulphate assimilation by glutathione in poplars (Populus tremula x P. alba) of wild type and overexpressing gamma-glutamylcysteine synthetase in the cytosol | Hartmann, T., Hönicke, P., Wirtz, M., Hell, R., Rennenberg, H. & Kopriva, S. | | | |
Regulation of sulfate uptake and expression of sulfate transporter genes in Brassica oleracea as affected by atmospheric H(2)S and pedospheric sulfate nutrition | Buchner, P., Stuiver, C.E., Westerman, S., Wirtz, M., Hell, R., Hawkesford, M.J. & De Kok, L.J. | | Plant Physiol: 136, 3396-3408 | |
Analysis of sequence, map position, and gene expression reveals conserved essential genes for iron uptake in Arabidopsis and tomato | Bauer, P., Thiel, T., Klatte, M., Bereczky, Z., Brumbarova, T., Hell, R. & Grosse, I. | | Plant Physiol: 136, 4169-4183 | |
Production of cysteine for bacterial and plant biotechnology: application of cysteine feedback-insensitive isoforms of serine acetyltransferase | | | | |
Discovery of an extended bundle sheath in Ricinus communis L. and its role as a temporal storage compartment for the iron chelator nicotianamine | Rutten, T., Kruger, C., Melzer, M., Stephan, U.W. & Hell, R. | | | |
Iron uptake, trafficking and homeostasis in plants | | | | |
A metal-binding member of the late embryogenesis abundant protein family transports iron in the phloem of Ricinus communis L | Kruger, C., Berkowitz, O., Stephan, U.W. & Hell, R. | | J Biol Chem: 277, 25062-25069 | |
Molecular and biochemical analysis of the enzymes of cysteine biosynthesis in the plant Arabidopsis thaliana | Hell, R., Jost, R., Berkowitz, O. & Wirtz, M. | | | |
Use of biomolecular interaction analysis to elucidate the regulatory mechanism of the cysteine synthase complex from Arabidopsis thaliana | Berkowitz, O., Wirtz, M., Wolf, A., Kuhlmann, J. & Hell, R. | | J Biol Chem: 277, 30629-30634 | |
The cysteine synthase complex from plants. Mitochondrial serine acetyltransferase from Arabidopsis thaliana carries a bifunctional domain for catalysis and protein-protein interaction | Wirtz, M., Berkowitz, O., Droux, M. & Hell, R. | | Eur J Biochem: 268, 686-693 | |
Plant concepts for mineral acquisition and allocation | Hell, R. & Hillebrand, H. | | Curr Opin Biotechnol: 12, 161-168 | |
Genomic and functional characterization of the oas gene family encoding O-acetylserine (thiol) lyases, enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana | Jost, R., Berkowitz, O., Wirtz, M., Hopkins, L., Hawkesford, M.J. & Hell, R. | | | |
Isolation and characterization of a gene for assimilatory sulfite reductase from Arabidopsis thaliana | Bork, C., Schwenn, J.D. & Hell, R. | | | |
Molecular physiology of plant sulfur metabolism | | | | |
Cysteine synthesis in plants: protein-protein interactions of serine acetyltransferase from Arabidopsis thaliana | | | | |
Structure of the gene encoding nitrilase 1 from Arabidopsis thaliana | Hillebrand, H., Tiemann, B., Hell, R., Bartling, D. & Weiler, E.W. | | | |
Cysteine biosynthesis in plants: isolation and functional identification of a cDNA encoding a serine acetyltransferase from Arabidopsis thaliana | Bogdanova, N., Bork, C. & Hell, R. | | | |
Isolation and characterization of two cDNAs encoding for compartment specific isoforms of O-acetylserine (thiol) lyase from Arabidopsis thaliana | Hell, R., Bork, C., Bogdanova, N., Frolov, I. & Hauschild, R. | | | |
An O-acetylserine (thiol) lyase cDNA from spinach | Hell, R., Schuster, G. & Gruissem, W. | | Plant Physiol: 102, 1057-1058 | |
lambda-Glutamylcysteine synthetase in higher plants: catalytic properties and subcellular localization | | | | |
