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Ingrid Lohmann Lab Publications

  • Pinto, P. B., Domsch, K., Gao, X., Wölk, M., Carnesecchi, J., & Lohmann, I. (2022). Specificity of the Hox member Deformed is determined by transcription factor levels and binding site affinities. Nature communications

  • Velten, J., Gao, X., Van Nierop Y Sanchez, P., Domsch, K., Agarwal, R., Bognar, L., Paulsen, M., Velten, L., & Lohmann, I. (2022). Single-cell RNA sequencing of motoneurons identifies regulators of synaptic wiring in Drosophila embryos. Mol Syst Biol

  • Carnesecchi, J., Boumpas, P., van Nierop Y Sanchez, P., Domsch, K., Pinto, H. D., Borges Pinto, P., & Lohmann, I. (2022). The Hox transcription factor Ultrabithorax binds RNA and regulates co-transcriptional splicing through an interplay with RNA polymerase II. Nucleic Acids Res

  • Folkendt, L., Lohmann, I., & Domsch, K. (2021). An Evolutionary Perspective on Hox Binding Site Preferences in Two Different Tissues. J Dev Biol
  • Paul, R., Giraud, G., Domsch, K., Duffraisse, M., Marmigère, F., Khan, S., Vanderperre, S., Lohmann, I., Stoks, R., Shashidhara, L. S., & Merabet, S. (2021). Hox dosage contributes to flight appendage morphology in Drosophila. Nat Commun
  • Domsch K, Schröder J, Janeschik M, Schaub C, Lohmann I. (2020) The Hox transcription factor Ubx ensures somatic myogenesis by suppressing the mesodermal master regulator Twist Cell Rep
  • Velten J, Agarwal R, van Nierop y Sanchez P, Bognar L, Paulsen M, Velten L, Lohmann I. (2020) The molecular logic of synaptic wiring at the single cell level. bioRxiv
  • Duffraisse M, Paul R, Carnesecchi J, Hudry B, Banreti A, Reboulet J, Ajuria L, Lohmann I, Merabet S. (2020) Role of a versatile peptide motif controlling Hox nuclear export and autophagy in the Drosophila fat body. J Cell Sci
  • Carnesecchi J, Lohmann I. (2020) Closing the gap: a roadmap to single-cell regulatory genomics. Mol Syst Biol
  • Sorge S, Theelke J, Yildirim K, Hertenstein H, McMullen E, Mu?ller S, Altbu?rger C, Schirmeier S, Lohmann I. (2020) ATF4-induced Warburg metabolism drives over-proliferation in Drosophila. Cell Rep
  • Carnesecchi J, Sigismondo G, Domsch K, Baader CEP, Rafiee MR, Krijgsveld J, Lohmann I. (2020) Multi-level and Lineage-Specific Interactomes of the Hox Transcription Factor Ubx Contribute to its Functional Specificity. Nat Comm
  • Domsch K, Carnesecchi C, Disela V, Friedrich J, Trost N, Ermakova O, Polychronidou M, Lohmann I. (2019) The Hox transcription factor Ubx stabilizes lineage commitment by suppressing cellular plasticity in Drosophila. eLife
  • Papagiannouli F, Fuller MT, Lohmann I. (2018) Nuclear export in somatic cyst cells controls cyst cell-germline coordination and germline differentiation in the Drosophila testis. bioRxiv
  • Trost N, Rempel E, Ermakova O, Tamirisa S, Pârc?l?bescu L, Boutros M, Lohmann JU, Lohmann I. (2018) WEADE: A Workflow for Enrichment Analysis and Data Exploration. PLoS One
  • Tamirisa S, Papagiannouli F, Rempel E, Ermakova O, Trost N, Zhou J, Mundorf J, Brunel S, Ruhland N, Boutros M, Lohmann JU, Lohmann I. (2018) Decoding the Regulatory Logic of the Drosophila Male Stem Cell System. Cell Rep
  • Carnesecchi J, Pinto PB, Lohmann I. (2018) Hox Transcription Factors: an overview of multi-step regulators of gene expression. Int J Dev Biol
  • Martins LR, Bung RK, Koch S, Richter K, Schwarzmüller L, Terhardt D, Kurtulmus B, Niehrs C, Rouhi A, Lohmann I, Pereira G, Fröhling S, Glimm H, Scholl C. (2017). Stk33 is required for spermatid differentiation and male fertility in mice. Dev Biol
  • Friedrich J., Sorge S., Bujupi F., Eichenlaub M.P., Schulz N.G., Wittbrodt J.  and Lohmann I. (2016). Hox Function is required for the Development and Maintenance of the Drosophila Feeding Motor Unit.  Cell Reports, Volume 14, Issue 4, p850–860, 2 February 2016.
  • Domsch, K., Papagiannouli, F., & Lohmann, I. (2015). The HOX-Apoptosis Regulatory Interplay in Development and Disease. Current topics in developmental biology
  • Papagiannouli F. and Lohmann I. (2015) Stage-specific control of stem cell niche architecture in the Drosophila testis by the postrior Hox gene Abd-B. Compt. Struct. Biotechnology, 13, 1122-130.
  • Merabet S. and Lohmann I. (2015) Towards a new twist in Hox and TALE DNA-binding Specificity. Developmental Cell, 32 (3), 1259-261.
  • Polychronidou M. and Lohmann I. (2014) Hox transcriptomics in Drosophila embryos. Methods in Molecular Biology, 1196, 197-208.
  • Papagiannouli F., Schardt L., Grajcarek J., Ha N. and Lohmann I. (2013) The Hox Gene Abd-B Controls Stem Cell Niche Function in the Drosophila Testis. Developmental Cell, Jan 27; 28 (2), 189-202.
  • Ha N., Polychronidou M. and Lohmann I. (2012) COPS: Detecting Co-Occurrence and Spatial Arrangement of Transcription Factor Binding Motifs in Genome-Wide Datasets. PLoS One, 7(12):e52055. doi: 10.1371/journal.pone.0052055. Epub 2012 Dec 18.
  • Polychronidou M. and Lohmann I. (2012) Cell-type specific cis-regulatory networks: Insights from Hox transcription factors. Fly (Austin), Dec 6;7(1).
  • Sorge S., Ha N., Polychronidou M., Friedrich J., Bezdan D., Kaspar P., Schaefer M.H., Ossowski S., Henz S.R., Mundorf J., Rätzer J., Papagiannouli F. and Lohmann I. (2012) The cis-regulatory code of Hox function in Drosophila. The EMBO Journal, Jul 10; 31(15):3323-33.
  • Gangishetti U., Veerkamp J., Bezdan D., Schwarz H., Lohmann I. and Moussian B. (2012) Grainy head and ecdysone cooperate during differentiation of the Drosophila skin. Insect Molecular Biology, Jun 21; (3):283-95.
  • Papagiannouli F. and Lohmann I. (2012) Shaping the niche: lessons from the Drosophila testis and other model systems. Biotechnology Journal, Jun; 7(6):723-36.
  • Zhai Z., Ha N., Papagiannouli F., Hamacher-Brady A., Brady N., Sorge S., Bezdan D. and Lohmann I. (2012) Antagonistic regulation of apoptosis and differentiation by the Cut transcription factor represents a tumor suppressing mechanism in Drosophila. PLoS Genetics 8(3): e1002582.
  • Zhai Z., Yang X. and Lohmann I. (2011) Functional dissection of the Hox protein Abdominal-B in Drosophila cell culture. Biochem. Biophys. Res. Comm. 414, 761-766.
  • Sancar G., Sancar C., Brügger B., Ha N., Sachsenheimer T., Gin E., Wdowik S., Lohmann I., Wieland F., Hoefer T., Diernfeller A. and Brunner M. (2011) A global circadian repressor controls anti-phasic expression of metabolic genes in Neurospora. Mol. Cell 44, 687-697.
  • Boy A. L., Zhai Z., Habring-Müller A. and Lohmann I. (2010) Vectors for efficient and high-throughput construction of fluorescent Drosophila reporters using the PhiC31 site-specific integration system. Genesis 48, 452-456.
  • Zhai Z., Fuchs A. L. and Lohmann I. (2010). Cellular analysis of newly identified Hox downstream genes in Drosophila. Eur. J. Cell Biol. 89, 273-78.
  • Zhai Z., Stein M. and Lohmann I. (2009). Expression of the apoptosis gene reaper in homeotic, segmentation and other mutants in Drosophila. Gene Expr. Patterns 9(5), 357-363.
  • Stöbe P., Stein, M. A. S., Habring-Müller, A., Bezdan, D., Fuchs, A. L., Hueber, S. D., Wu, H. and Lohmann I. (2009) Multifactorial regulation of a Hox target gene. PLoS Genet. 5(3): e1000412.
  • Hueber, S. D. and Lohmann I. (2008). Shaping segments: Hox gene function in the genomic age. Bioessays 30, 965-979.
  • Hueber, S. D., Bezdan, D., Henz, S. R., Blank, M.,Wu, H. and Lohmann, I.(2007). Comparative analysis of Hox downstream genes in Drosophila. Development 134, 381-392.
  • Lohmann I.(2006). Hox genes: realising the importance of realisators. Curr. Biol. 16, R988-R989.
  • Lohmann I. (2003). Dissecting the regulation of the Drosophila cell death activator reaper. Gene Expr. Patterns3, 159-163.
  • Lohmann I., McGinnis, N., Bodmer, N. and McGinnis W. (2002). The Drosophila Hox gene Deformed sculpts head morphology via direct regulation of the apoptosis activator reaper. Cell 110, 457-466.
  • Lohmann I. and McGinnis W. (2002). Hox genes: It’s all a matter of context. Curr. Biol. 10, R514-R516.
  • Lohmann, J. U., Endl, I. and Bosch T. C. G. (1999). Silencing of developmental genes in Hydra. Dev. Biol. 214, 211-214.
  • Endl I., Lohmann J. U. and Bosch T. C. G. (1999). Head-specific gene expression in Hydra: complexity of DNA-protein interactions at the promoter of ks1 is inversely correlated to the head activation potential. Proc. Natl. Acad. Sci. U S A 96, 1445-1450.
  • Endl I., Konzok A. and Nellen W. (1996). Antagonistic effects of signal transduction by intracellular and extracellular cAMP on gene regulation in Dictyostelium. Mol. Biol. Cell 7, 17-24.

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